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Don'twashthosefossils!

StandardmuseumpracticecanwashawayDNA.

1.Washing,brushingandvarnishingfossils—allstandardconservationtreatmentsusedbymanyfossilhuntersandmuseumcuratorsalike—vastlyreducesthechancesofrecoveringancientDNA.

2.Instead,excavatorsshouldbehandlingatleastsomeoftheirbountywithgloves,andfreezingsamplesastheyarefound,dirtandall,concludesapaperintheProceedingsoftheNationalAcademyofSciencestoday.

3.AlthoughmanypalaeontologistsknowanecdotallythatthisisthebestwaytouptheoddsofextractinggoodDNA,Eva-MariaGeigloftheJacquesMonodInstituteinParis,France,andhercolleagueshavenowshownjusthowimportantconservationpracticescanbe.Thisinformation,theysay,needstobehammeredhomeamongthepeoplewhoareactuallyoutinthefielddiggingupbones.

4.Geiglandhercolleagueslookedat3,200-year-oldfossilbonesbelongingtoasingleindividualofanextinctcattlespecies,calledanaurochs.ThefossilsweredugupatasiteinFranceattwodifferenttimes—eitherin1947,andstoredinamuseumcollection,orin2004,andconservedinsterileconditionsat-20oC.

5.Theteam'sattemptstoextractDNAfromthe1947bonesallfailed.Thenewlyexcavatedfossils,however,allyieldedDNA.

6.Becausetheboneshadbeenburiedforthesameamountoftime,andinthesameconditions,theconservationmethodhadtobetoblamesaysGeigl."AsmuchDNAwasdegradedinthese57yearsasinthe3,200yearsbefore,"shesays.

Washin,washout

7.Becausemanypalaeontologistsbasetheirworkontheshapeoffossilsalone,theirmethodsofconservationarenotdesignedtopreserveDNA,Geiglexplains.

8.Thebiggestproblemishowtheyarecleaned.Fossilsareoftenwashedtogetheron-siteinalargebath,whichcanallowwater—andcontaminantsintheformofcontemporaryDNA—topermeateintotheporousbones."NotonlyistheauthenticDNAgettingwashedout,butcontaminationisgettingwashedin,"saysGeigl.

9.MostancientDNAspecialistsknowthisalready,saysHendrikPoinar,anevolutionarygeneticistatMcMasterUniversityinOntario,Canada.Butthatdoesn'tmeanthatbestpracticehasbecomewidespreadamongthosewhoactuallyfindthefossils.

10.GettingholdoffossilsthathavebeenpreservedwiththeirDNAinmindreliesoncloserelationshipsbetweenlab-basedgeneticistsandtheexcavators,sayspalaeogeneticistSvantePbooftheMaxPlanckInstituteforEvolutionaryAnthropologyinLeipzig,Germany.Andthatonlyoccursinexceptionalcases,hesays.

11.Pbo'steam,whichhasbeensequencingNeanderthalDNA,continuallyfacestheseproblems."WhenyouwanttostudyancienthumanandNeanderthalremains,there'sabigissueofcontaminationwithcontemporaryhumanDNA,"hesays.

12.Thisdoesn'tmeanthatallmuseumspecimensarefatallyflawed,notesPbo.TheNeanderthalfossilsthatwererecentlysequencedinhisownlab,forexample,hadbeenpartofamuseumcollectiontreatedinthetraditionalway.ButPboiskeentoseesamplesoffossilsfromeverymajorfindpreservedinlinewithGeigl'srecommendations—justincase.

Warmandwet

13.Geiglherselfbelievesthat,withcooperationbetweenbenchandfieldresearchers,preservingfossilsproperlycouldopenupavenuesofdiscoverythathavelongbeenassumedclosed.

14.Muchhumanculturaldevelopmenttookplaceintemperateregions.DNAdoesnotsurvivewellinwarmenvironmentsinthefirstplace,andcanvanishwhenfossilsarewashedandtreated.Forthisreason,Geiglsays,mostancientDNAstudieshavebeendoneonpermafrostsamples,suchasthewoollymammoth,oronremainsshelteredfromtheelementsincoldcaves—includingcavebearandNeanderthalfossils.

15.Betterconservationmethods,andafocusonfreshfossils,couldboostDNAextractionfrommoredelicatespecimens,saysGeigl.Andthatcouldshedmorelightonthestoryofhumanevolution.

(640wordsnature)

Glossary

Palaeontologists古生物學(xué)家

Aurochs歐洲野牛

Neanderthal(人類學(xué))尼安德特人，舊石器時代的古人類。

Permafrost(地理)永凍層

Questions1-6

AnswerthefollowingquestionsbyusingNOMORETHANTHREEWORDSforeachanswer.

1.Howdidpeopletraditionallytreatfossils?

2.WhatsuggestionsdoGeiglandhercolleaguesgiveonwhatshouldbedonewhenfossilsarefound?

3.Whatproblemsmaybeposediffossilbonesarewashedon-site?NameONE.

4.WhatcharacteristicdofossilboneshavetomakethemsusceptibletobecontaminatedwithcontemporaryDNAwhentheyarewashed?

5.Whatcouldbebetterunderstoodwhenconservationtreatmentsareimproved?

6.Thepassagementionedseveralanimalspeciesstudiedbyresearchers.Howmanyofthemarementioned?

Questions7-11

Dothefollowingstatementsagreewiththeinformationgiveninthepassage?PleasewriteTRUEifthestatementagreeswiththewriterFALSEifthestatementdoesnotagreewiththewriterNOTGIVENifthereisnoinformationaboutthisinthepassage.

7.IntheirpaperpublishedintheProceedingsoftheNationalAcademyofSciences，GeiglandhercolleagueshaveshownwhatconservationpracticesshouldbefollowedtopreserveancientDNA.

8.ThefossilbonesthatGeiglandhercolleaguesstudiedareallfromthesameaurochs.

9.Geneticistsdon'thavetoworkonsite.

10.OnlynewlyexcavatedfossilbonesusingnewconservationmethodssuggestedbyGeiglandhercolleaguescontainancientDNA.

11.Paaboisstillworriedaboutthepotentialproblemscausedbytreatmentsoffossilsintraditionalway.

Questions12-13

CompletethefollowingthestatementsbychoosingletterA-Dforeachanswer.

12.“Thisinformation”inparagraph3indicates:

[A]ItiscriticaltofollowproperpracticesinpreservingancientDNA.

[B]ThebestwayofgettinggoodDNAistohandlefossilswithgloves.

[C]Fossilhuntersshouldwearhome-madehammerswhilediggingupbones.

[D]Manypalaeontologistsknowhowoneshoulddointreatingfossils.

13.ThestudyconductedbyGeiglandhercolleaguessuggests:

[A]thefactthatancientDNAcannotberecoveredfromfossilbonesexcavatedinthepast.

[B]thecorrelationbetweentheamountofburyingtimeandthatoftherecoveredDNA.

[C]thepaceatwhichDNAdegrades.

[D]thecorrelationbetweenconservationpracticesanddegradationofDNA.

WhichjobatHudsonswillPamapplyfor。

Getoffthetreadmill

SectionB

Directions:Therearetenblanksinthefollowingletter.YouarerequiredtochoosethebestonefromthegivenfourchoicesmarkedA,B,C,andD.Thenwritedownthecorrectanswerinthebrackets.Thissectiontotals10points,onepointforeachblank.

DearMr.Bush

Thankyouforyour1ofJanuary5forourBeautyBrandBlouses.

Wearenowexporting2ofvariousbrands,amongwhichBeautyBrandisthemostfamous.Theyareingreat3abroadandourstocksarerunning4quickly.Theyarepopularnotonlyfortheirnoveldesign,butalsoforthereasonableprices.Weareconfidentthatonceyouhavetriedourblouses,youwillplacerepeatorderswithus5largequantities.

Asyourequested,wearenow6asfollows:

Price:US$600perdozenCIFNewYork

TermsofPayment:BysightL/Ctobeopenedthroughabanktobe7bytheSellers.

Shipment:InMarch2007.

Pleasenotethatwedonotallowanycommission8ourblouses,butadiscountof5%maybe9ifthequantityismorethan1,000dozen.

Theaboveofferismadewithout10andissubjecttoourfinalconfirmation.

Wehopethatyouwillplaceanorderwithusatanearlydate.

Sincerelyyours

()1.A.requestB.enquiryC.acquisitionD.requirement

()2.A.blousesB.womanblousesC.womanshirtsD.ladyshirts

()3.A.needB.wantC.requireD.demand

()4.A.upB.offC.downD.away

()5.A.atB.forC.inD.with

()6.A.orderingB.offeringC.placingD.advising

()7.A.agreedB.approvedC.acceptableD.covered

()8.A.onB.inC.ofD.at

()9.A.providedB.suppliedC.furnishedD.granted

()10.A.promiseB.dutyC.engagementD.onus

Whatmakesameetingeffective?