美[nɑ:t?] 1 . The quality of the food here has dropped a notch recently.
這里的飯菜質量最近下降了一級。
來自《權威詞典》
2 . He is keen to notch up yet another success.
他渴望能再次成功.
來自《簡明英漢詞典》
3 . A sesame stalk puts forth blossoms notch by notch, higher and higher.
芝麻開花節節高.
來自《現代漢英綜合大詞典》
4 . The peanuts they grow are top - notch .
他們種的花生是 拔尖 的.
來自《現代漢英綜合大詞典》
5 . In this country the good players are pulled down a notch or two.
在這個國家，優秀選手的水平降了一兩個檔次。
來自柯林斯例句
1.a V-shaped indentation;
mandibular notch
2.the location in a range of mountains of a geological formation that is lower than the surrounding peaks;
we got through the pass before it started to snow
3.a V-shaped or U-shaped indentation carved or scratched into a surface;
there were four notches in the handle of his revolver
4.a small cut
1.cut or make a notch into;
notch the rope
2.notch a surface to record something
簡介 Notch信號傳導途徑在無脊椎動物和脊椎動物中廣泛存在且高度保守。此途徑介導由局部細胞間相互作用而產生的、對多種不成熟細胞分化的抑制信號， 在胚胎發育中起重要作用。哺乳類動物中Notch途徑的功能復雜多樣， 參與造血、T細胞發育、血管生成等重要生理過程，并與腫瘤形成和某些神經系統疾病有密切關系。 研究證實sirt1對內源性Notch反應起到變阻器的作用。 在多細胞生物的發育中， 需要通過鄰近細胞間的相互作用對各譜系細
